Hyperthermia is a state of higher temperature of the body, to which an organism reacts with thermoregulatory mechanisms. In oncology, artificial hyperthermia is used to increase, with specialized equipment, the tissue temperature, which makes cancer cells more sensitive to ionizing radiation and certain anti-cancer drugs. In practice the temperature of 40°C to 43°C is used. Most commonly used is high frequency radio, microwave or infrared radiation. Hyperthermia is considered the fourth weapon in the battle with cancer, after surgery, radiotherapy and chemotherapy.
With the use of chemotherapy or radiotherapy
Local hyperthermia treatments used alone or in combination with radio or chemotherapy treatments allow to reduce the weight of the tumor, giving a chance to extend the time of disease recurrence or allow for the operability of the tumor.
The results of many clinical trials evaluating the effectiveness of combining hyperthermia with radiotherapy prove that it can make cancer cells more sensitive to radiation, and in combination with chemotherapy enhance the cytotoxic effects on cancer cells. In the European Health Centre in Otwock the most common hyperthermia treatment is performed in patients with recurrent breast cancer after mastectomy.
Hyperthermia treatments are non-invasive, non-toxic, well tolerated and do not require hospitalization. Currently used modern equipment, in addition to high efficiency, is safe for the patient by controlling the temperature of the diseased tissue and the surrounding healthy tissue. The ALBA ON 4000 features a high performance hydraulic system for cooling while delivering high system responsiveness and high sensitivity of the temperature measuring electrodes.
Used in clinical centers
Hyperthermia treatments are currently available worldwide in many clinical research centers and private clinics, mainly in the Netherlands, Switzerland, Austria, Germany, Italy, North America, China and Japan. In Poland, local hyperthermia devices are used in 9 clinical centers, the most modern of which is in the European Health Center Otwock, F. Chopin Hospital in Otwock.
Over the past 25 years, dozens of reports have been published on randomized clinical trials evaluating the efficacy of hyperthermia in combination with radiotherapy and chemotherapy for the treatment of sarcoma, melanoma, head and neck, brain, lung, esophagus, breast, bladder, rectum, liver, ovary, cervix, uterus and skin cancers. The results of this research indicate the significant benefits of this method. For example, better local control (CR) of melanoma from 35% to 62% (1), breast cancer from 41% to 59% (2) and 42% to 66% (3), cervical carcinoma from 57% to 83% (4).
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